Optimizing Lumbar Spinal Fusion with Cellular Technologies

Аннотация

Degenerative-dystrophic diseases of the lumbar spine (DDSD) are a leading cause of temporary and permanent
disability, with significant advancements in surgical methods to address them. One crucial aspect of lumbar spinal fusion
is the choice of bone grafting material, and the trend toward minimally invasive surgery has intensified the need for effective
alternatives to autologous bone. This research explores the potential of cellular technologies, specifically concentrated
bone marrow aspirate (BMC), to enhance the outcomes of minimally invasive lumbar fusion for DDSD. The study
aims to comprehensively investigate the clinical and radiological results of spinal fusion using autologous bone, artificial
bone substitutes, and BMC. It also involves the development of a technology for obtaining and utilizing BMC to augment
interbody bone block formation. The findings provide insight into the effectiveness of cellular technologies in improving
the success rates of spinal fusion and reducing specific negative radiological outcomes. This research is significant as
it pioneers the use of BMC in enhancing minimally invasive interbody spinal fusion and offers practical implications for
improving patient outcomes in the treatment of DDSD.